Mitochondrial respiratory chain deficiency inhibits lysosomal hydrolysis
نویسندگان
چکیده
منابع مشابه
Acute and chronic mitochondrial respiratory chain deficiency differentially regulate lysosomal biogenesis
Mitochondria are key cellular signaling platforms, affecting fundamental processes such as cell proliferation, differentiation and death. However, it remains unclear how mitochondrial signaling affects other organelles, particularly lysosomes. Here, we demonstrate that mitochondrial respiratory chain (RC) impairments elicit a stress signaling pathway that regulates lysosomal biogenesis via the ...
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ژورنال
عنوان ژورنال: Autophagy
سال: 2019
ISSN: 1554-8627,1554-8635
DOI: 10.1080/15548627.2019.1586256